PhD in Bioinformatics, Scientist in Antibody Development
A branch of protein bioinformatics looks at the sequence-structure relationship between protein structures and their encoding sequences. This is most prominent in homology modelling, where we align a query sequence to a database of sequences with known structures, pick the hit with the highest similarity and cast the structure to the query sequence. These different steps can be a field on its own: sequence alignment, similarity measure and structural remodelling. Here I mention a number of tools used in my current research group: