PhD in Bioinformatics, Scientist in Antibody Development
Apart from on-target binding, antibodies also have other parts that need to be engineered before they develop into a drug. This is particularly tricky for the plethora of fusion antibodies that are non-natural. Here I jotted down some notes as I read around this topic.
This blog post covers the basic commands, data cleaning and analysis angles for scBCR datasets and transcriptomic studies.
Happy days – pleased to share our latest paper supplied with a nice webserver!
https://www.blopig.com/blog/2020/03/tcrbuilder-multi-state-t-cell-receptor-structure-prediction/
Here is a quick summary of my recently accepted paper!
https://www.blopig.com/blog/2019/10/comparative-analysis-of-the-cdr-loops-of-antigen-receptors/
I was testing out all the possible ways to improve the performance of hashing and matching for the Ligity paper. Here is one of the cases where I benchmarked a bloom filter: